Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of many myeloma. Its synthesis or analyze is important for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound during the synthesis of imatinib, a drug that targets distinct kinds of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is essential for optimizing the output method and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to treat breast cancer, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Utilized in the procedure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis CAS NO.61259-48-1 of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the therapy of colorectal cancer and modest cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, including antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be used in foods, (4S pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication applied to control variety 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).